So, storing sorafenib, that cancer drug we often use, It is of great significance to maintain stability in liquid state. Sorafenib? It’s this kinase inhibitory substance that’s highly sensitive to light and Moisture levels. They can render it ineffective pretty fast.

So, Determine the optimal method to store it—significant matter for the drug’s effectiveness and safety. Within this article, I will discuss Five crucial points During the storage of sorafenib in its liquid form. By the way, Just my personal opinion from managing this issue.

sorafenib base storage in solution

Temperature Control

Maintaining Ambient Temperature constancy is crucial when it comes to storing sorafenib properly. According to some study, the optimal Ambient Temperature for sorafenib is At Ambient Temperatures ranging from 2 to 8 degrees Celsius.

Hence, many pharmaceutical companies keep it Keep chilledd, By the way, store it in a refrigerator. Well, there was a place I worked at that didn’t Keep chilled it. It became spoiled in just a few weeks—major setback. This experience showed me that Maintaining a constant Ambient Temperature is key for sorafenib storage.

sorafenib base storage in solution

Container Selection

And man, the type of container you select is equally important. Since it’s photosensitive, amber glass or those sophisticated plastic containers are usually the way to go to protect it from ultraviolet radiation.

Research says using these containers can actually extend the lifespan of sorafenib, up to a year! I recall a time I used a translucent plastic container for sorafenib. It turned to crap real quick. From then on, I’ve been super careful with the containers I use.

sorafenib base storage in solution

Desiccant Use

And don’t let moisture reach or affect it either—it’s no good. To safeguard it, it is common practice to use such as silica gel in the storage container.

Research says using stuff like silica gel really helps prevent it from going bad. Anecdotally, I’ve seen it last longer when you use desiccant.

sorafenib base storage in solution

Shelf-Life Determination

Figuring out how to how long it’s good for is extremely important too. The team from the European Medicines Agency say it lasts about two years when when properly stored.

But it varies by each batch, you see? You need to monitor it and discard the items that appear to be in poor condition.

sorafenib base storage in solution

Handling and Disposal

And by the way, proper handling and disposal are crucial for safety. It’s recommended to use gloves while dealing with it and adhere to the guidelines for disposal.

Studies indicate that discarding it incorrectly, it can harm the natural surroundings. I once witnessed someone putting it in the regular trash. That was a significant wake-up call regarding the proper handling and disposal of it.